BPC-157
Body Protection Compound-157 | Pentadecapeptide
On this page
What is BPC-157?
BPC-157 is a lab-made peptide, a short chain of amino acids, modeled on a protective protein the body naturally makes in the stomach lining. In animal studies, researchers have looked at how it behaves in tissue-repair pathways, from tendons and muscle to the gut lining. It's sold here strictly as a research chemical for laboratory study, not for use in people or animals.
Key terms:
BPC-157 is a synthetic pentadecapeptide.
BPC-157 is a lab-made peptide of 15 amino acids. Its sequence comes from a protective protein found in human stomach juice. It has a large preclinical research record covering tissue repair, inflammation, and protection of the gut lining. Most of that work comes from animal-model studies.
Key research areas
- Studied in preclinical models for effects on tendon, ligament, muscle, and bone healing
- Investigated for localized anti-inflammatory and tissue-targeting effects following injectable administration
- Promotes angiogenesis and formation of new blood vessels
- Enhances collagen synthesis
- Gastrointestinal protection
- Localized tissue repair
Researched dosing
This table shows how researchers structure laboratory study designs with BPC-157, the dose ranges and schedules used in published studies, presented as research-methodology reference, not usage instructions.
| Phase | Dose | Frequency | Route |
|---|---|---|---|
| Tendon and joint healing models | 250-500mcg | 1-2x daily | SubQ near injury |
| Major-injury models | 500-1000mcg | 2x daily | SubQ near injury |
| General healing models | 250-500mcg | 1-2x daily | SubQ or IM |
| Maintenance | 250mcg | 1x daily | SubQ |
Commonly cycled 12 weeks on, 4+ weeks off.
How it works
At the cell level, BPC-157 research looks at how the peptide signals cells involved in blood-vessel formation and tissue repair, the terms below (angiogenesis, collagen synthesis) are just the biology names for those processes.
Injectable BPC-157 provides direct tissue targeting and higher local concentrations. Promotes angiogenesis (formation of new blood vessels), enhances collagen synthesis, modulates growth factor expression, and provides localized protection against tissue damage.
Molecular data
These figures, molecular weight, chain length, sequence, are the chemistry fingerprint researchers and lab technicians use to confirm a sample really is BPC-157 and to handle it correctly; no chemistry background needed to read them.
- Weight
- 1419.53 Da
- Length
- 15 amino acids
- Type
- Pentadecapeptide
Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
Pharmacokinetics
This chart shows how a research dose of BPC-157 is absorbed and cleared over time in animal studies, read it like a timer: the peak is when levels are highest, then the curve trails off as the compound clears.
- Peak
- 1 hr
- Half-life
- 4 hrs
- Cleared
- ~20 hrs
Sikiric et al. various studies
What the studies report
This section lists the body systems and research areas scientists have investigated for BPC-157, a summary of what's been studied in the literature, not medical claims about people.
Wound Healing
In animal injury models, localized injection was associated with faster tendon-to-bone healing and improved biomechanical properties. Animal studies of crush injuries and surgical procedures reported faster muscle healing and shorter recovery times with direct tissue targeting, along with increased blood vessel formation and vascularization at injury sites.
Neurological
Studied for neuroprotective and neurological-recovery effects in animal models, via mechanisms including angiogenesis and growth-factor modulation.
Gastrointestinal
Derived from a human gastric-juice protective protein; animal studies report cytoprotective effects and improved mucosal healing in gastric ulcer models.
Dosage reference
- Doses used in research
- 250-500 mcg
- Frequency in studies
- 1-2x daily
- Handling
- Reconstituted solution, research use only; not for administration
- Timeline reported in studies
- 1-3 weeks for healing, 3-7 days for inflammation
- Storage
- Fridge 2-6°C, use within 28 days
- Cycle length
- 4-12 weeks
- Break between cycles
- 4+ weeks
Interactions
This list shows which other peptides researchers have studied alongside BPC-157, and why, several recovery-focused peptides show up often in the same preclinical study designs.
Reconstitution & storage
This is the standard laboratory method for turning freeze-dried BPC-157 powder into a liquid research solution, the same basic water-based mixing process used for most peptide research.
- Clean work area and hands thoroughly
- Calculate required BAC water volume using calculator below
- Draw BAC water into syringe
- Inject slowly down vial side (not directly onto powder)
- Gently swirl until dissolved (never shake)
- Store the reconstituted solution refrigerated (2-8°C), labeled with the date and concentration, for laboratory research use only.
Lyophilized: -20°C or colder, use within Multiple years when sealed and protected from light
Reconstituted: 2-6°C, use within 28 days
Open the BPC-157 reconstitution calculatorQuality indicators
These are the visual and lab-report checks researchers use to confirm a BPC-157 sample is pure and correctly identified before it goes into a study, a quick sanity check against the Certificate of Analysis (COA), not a guarantee.
White, Fluffy Cake - Lyophilized powder should appear as a white, fluffy "cake" that fills most of the vial bottom. This indicates proper freeze-drying.
Clear Solution After Reconstitution - When properly mixed with BAC water, solution should be crystal clear with no particles or cloudiness.
Slight Clumping - Small clumps that dissolve completely with gentle swirling are acceptable. Shipping can cause minor compaction.
Collapsed or Melted Appearance - If powder appears collapsed, melted, or stuck to vial sides, it may have been exposed to heat during shipping.
Cloudy After Reconstitution - Persistent cloudiness, particles, or precipitates after gentle mixing indicate degraded or contaminated peptide.
What to expect
This timeline summarizes what animal-model research literature has reported at each stage of a study, research context for comparing studies, not a personal-results promise.
Animal studies reported reduced inflammation at the administration site
Animal studies reported faster healing rates and improved tissue repair
Peak localized tissue-repair effects reported in the animal literature
Safety notes
This section covers how BPC-157 is regulated and handled in a laboratory setting, research-use-only scope, storage cautions, and regulatory status, not medical safety advice for people.
- May cause mild injection site reactions
- Not recommended during pregnancy or breastfeeding
- Not FDA approved
- WADA prohibited (S0: Non-Approved Substances) - not for competitive athletes; added 2022, no TUE available for athletes
Regulatory status
- Not approved by the FDA for any indication.
- Prohibited by the World Anti-Doping Agency (WADA), added to the Prohibited List in 2022 (category S0).
- Supplied and described for laboratory research use only, not for human or veterinary use.
What is not known
The limits of the published work on BPC-157, stated plainly. Research use only: none of this is guidance for a person.
Almost every result on this page comes from rats. Animal work does not show what would happen in a person, and the published human work is limited to small early trials.
The animal studies used several different routes, given by mouth, into the muscle, or near the injury. A result from one route does not show what another route would do.
The safety study behind the no serious effects line was run in mice, rats, rabbits and dogs. It does not show a safe dose for a person, and no such dose is known.
How the peptide reaches a healing tendon when it is given somewhere else is not measured. The papers name a mechanism, and none of them tracks the molecule to the injury.
What happens after dosing stops is not known from the papers cited here.
The terms, in plain words
Every technical term this page leans on, said again in ordinary words.
- Pentadecapeptide
- A chain of fifteen amino acids. That is all the word means.
- Cytoprotective
- Protects cells from damage, as measured in that study.
- Angiogenesis
- The growing of new small blood vessels.
- Gastric juice
- The acid fluid in the stomach. The protein this peptide is modelled on was found there.
- Lyophilized
- Freeze dried into a dry cake, which is the form the powder ships in.
Frequently asked questions
What is BPC-157?
BPC-157 is a synthetic pentadecapeptide, a chain of 15 amino acids, modeled on a protective protein found in human gastric juice. In the research literature it carries a substantial preclinical profile across tissue-repair, inflammation, and gastrointestinal-protection pathways, studied primarily in animal models. Lux BioPure supplies it strictly as a research chemical for laboratory study, not for use in people or animals.
How is BPC-157 typically reconstituted for research use?
In laboratory settings, lyophilized BPC-157 powder is reconstituted with bacteriostatic water: the diluent is added slowly down the vial wall rather than onto the powder, then the vial is gently swirled, never shaken, until the solution is clear. The reconstituted research solution is then labeled with its date and concentration and refrigerated. This is standard peptide-handling methodology, not a usage instruction.
How should reconstituted BPC-157 be stored in the lab?
Lyophilized BPC-157 stays stable for years when sealed, kept at -20°C or colder, and protected from light. Once reconstituted with bacteriostatic water, the solution should be kept refrigerated at roughly 2-6°C and used within about 28 days. Researchers confirm a good sample by its white, fluffy lyophilized cake and a clear, particle-free solution after gentle mixing.
Is BPC-157 legal to purchase for research in Canada?
Lux BioPure sells BPC-157 in Canada strictly as a research-use-only chemical for laboratory study, it is not for human or veterinary use and is not offered as a drug or supplement. BPC-157 is not an approved drug, and it appears on the World Anti-Doping Agency prohibited list (category S0), so it is not permitted for competitive athletes.
Sources
The published work behind this entry. Each link was opened and each note says what that paper reports, not what it suggests.
- Protective effects of pentadecapeptide BPC 157 on gastric ulcer in rats World Journal of Gastroenterology, 2004Rats. Reports faster healing of induced stomach ulcers, given either into the stomach or into the muscle.
- Preclinical safety evaluation of body protective compound-157, a potential drug for treating various wounds Regulatory Toxicology and Pharmacology, 2020Mice, rats, rabbits and dogs. A toxicity study, not an effectiveness study. It reports no effects it could attribute to the compound at the doses tested.
- Stable gastric pentadecapeptide BPC 157 can improve the healing course of spinal cord injury and lead to functional recovery in rats Journal of Orthopaedic Surgery and Research, 2019Rats with a spinal cord injury. Reports better movement in the treated group over the follow up.
How it is studied
In the published studies listed below. Each one names the species it was run in, the dose, how long it ran, and what it reported.
Cytoprotective effects against gastric ulcers through multiple mechanisms including cytoprotection and enhanced mucosal healing.
View StudyNo serious adverse effects at therapeutic doses, establishing safety profile for potential clinical applications.
View StudySignificant functional recovery, reduced tissue damage, and improved neurological outcomes in spinal cord injury models.
View Study